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Metabolic Profiling Blood Test (Amino Acids)

Metabolic Profiling Blood Test (Amino Acids)

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The Metabolic Profiling - Amino Acids test provides detailed insight into your levels of specific amino acids. Amino acids are the building blocks of proteins, meaning they are essential to all body functions including normal maintenance and repair of tissues and the healthy function of all organs.

Deficiencies in certain amino acids can cause a variety of problems ranging from neurotransmitter deficiencies that can lead to depression, anxiety, insomnia, and increased perception of pain, to energy metabolism problems that can lead to fatigue or muscle weakness.

In both Long Covid and ME/CFS, imbalances in amino acids have been observed. For instance, disturbances to arginine metabolism (observed in Long Covid patients) are thought to contribute to endothelial dysfunction and immune dysregulation.

Identifying these imbalances can allow practitioners to personalise dietary modifications, supplementation or other lifestyle changes that can compensate, supporting healing and improved quality of life.

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Markers Included In The Test

Alanine: Alanine is a key player in glucose metabolism and serves as a vital energy source for muscles and the central nervous system. Abnormal levels can indicate metabolic disturbances or diseases such as liver disease, diabetes, or heart failure.

Arginine : Arginine is a vital amino acid involved in protein synthesis, hormone release, cell division, and the production of nitric oxide, which widens blood vessels and improves blood flow. Disruptions in arginine levels can be associated with cardiovascular disease, certain types of cancer, erectile dysfunction, weakened immune system, poor wound healing and hair loss.

Glutamine: Glutamine is the most abundant amino acid in the blood and is involved in many metabolic processes. Abnormally high levels can be a sign of certain genetic disorders or liver disease, while low levels may suggest a glutamine deficiency, which can weaken the immune system and affect gut health.

Glycine: Glycine is a non-essential amino acid that aids in the production of proteins and detoxification due to its involvement in the synthesis of a powerful antioxidant called glutathione. It also plays a vital role in the nervous system. Abnormally low levels can lead to issues such as fatigue, poor cognitive function, digestive complications and other problems.

Histidine: Histidine is an essential amino acid that helps in the production of histamine, an important neurotransmitter involved in immune responses, gastric acid secretion, and neurological function. Abnormal levels of histidine could reflect issues with protein intake or metabolism.

Isoleucine: Isoleucine is an essential branched-chain amino acid crucial for energy regulation, wound healing, immune function, and hemoglobin synthesis. Abnormally high or low levels can indicate metabolic disorders and potentially contribute to symptoms such as muscle weakness, fatigue

Leucine: Leucine is an essential amino acid crucial for protein synthesis and muscle repair. It also helps regulate blood sugar levels. Abnormally high or low levels can indicate metabolic or nutritional issues and may impact muscle function and overall health.

Lysine: Lysine is an essential amino acid that plays key roles in energy production and calcium absorption, aiding in muscle growth. Imbalances can lead to symptoms such as fatigue, nausea, and muscle weakness.

Methionine: Methionine is an essential amino acid that plays a key role in protein synthesis and the production of S-adenosylmethionine (SAMe), a compound involved in a variety of bodily functions including mood regulation and immune function. Abnormally high or low levels of methionine can indicate issues with protein metabolism, potentially leading to a range of symptoms such as muscle weakness, fatigue, and mood changes.

Phenylalanine: Phenylalanine is an essential amino acid that is required for protein synthesis and plays a key role in producing other amino acids. Low levels can lead to decreased mental energy and mood issues such as depression.

Serine: Serine is an amino acid involved in protein synthesis, cellular growth, DNA maintenance, and cognitive function. It contributes to the production of certain neurotransmitters that influence mood. Altered serine metabolism has been linked to various health conditions, including cardiovascular diseases and neurological disorders like Alzheimer's disease.

Taurine: Taurine is an amino acid that aids in hydration, electrolyte balance, and neurological function. It plays a significant role in vision and supporting the immune system, and research suggests it may help protect against heart disease. Abnormal levels can be linked to various health problems including cardiovascular disease, neurological disorders, and diabetes.

Threonine: Threonine is an essential amino acid that plays an important role in the healthy function of the central nervous system, liver, and immune system. It also supports cardiovascular health and aids in the production of antibodies, making it key for a well-functioning immune system.

Tryptophan: Tryptophan is an essential amino acid that plays a crucial role in the production of serotonin, a neurotransmitter important for mood regulation and sleep. Abnormal levels can potentially affect mood, sleep, and overall mental health, and are linked to disorders such as depression and anxiety.

Tyrosine: Tyrosine is an amino acid involved in the production of several important substances in the body, including the neurotransmitters dopamine, norepinephrine, and epinephrine, which regulate mood and stress response. Abnormal levels of tyrosine can be associated with conditions such as depression and stress.

Valine: Valine is a branched-chain essential amino acid important in muscle metabolism, repair, and growth. Abnormal levels can affect muscle coordination and energy production.

Glutamic acid: Glutamic acid is a non-essential amino acid involved in various metabolic processes. It plays a role in protein synthesis and serves as a neurotransmitter in the brain, contributing to cognitive functions such as learning and memory. Research has explored links between abnormal levels of glutamic acid and various health conditions. For instance, high levels may be associated with neurological conditions like epilepsy, while low levels might be connected to fatigue and cognitive impairment