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Autoimmunity Blood Test

Autoimmunity Blood Test

Regular price £89.00 GBP
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The Secondary Autoimmunity Screen tests for autoantibodies that are associated with various autoimmune diseases. Autoantibodies target and bind to your own tissues, triggering the immune system to attack your body.

Evidence from several large studies has shown that Covid infection causes an increase in the likelihood of developing a new autoimmune disease. Most autoimmune diseases only become symptomatic when they are already advanced, but many are detectable long before they become symptomatic.

This test is a general autoimmunity screen, and while it can identify some specific autoimmune diseases, it is important to note that it tests for several antibodies that can be present in more than one specific disease. Positive results will be interpreted by one of our clinicians who will advise about what to do next.

Autoimmune diseases associated with these markers:

  • Hashimoto's thyroiditis
  • Graves' disease
  • Other thyroid autoimmune diseases
  • Systemic Lupus Erythematosus (SLE)
  • Sjogren's Syndrome
  • Rheumatoid Arthritis
  • Scleroderma
  • Primary Biliary Cirrhosis
  • Autoimmune Hepatitis
  • Autoimmune HepatitisType 2
  • Autoimmune Cholangitis
  • Pernicious Anaemia
  • Atrophic Gastritis
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Markers Included In The Test

Antinuclear Antibodies: Antinuclear Antibodies (ANAs) are a group of autoantibodies that target the nucleus of cells. Their presence in high levels can indicate autoimmune diseases such as lupus or rheumatoid arthritis.

Gastric Parietal Cell Antibodies: This test checks for antibodies that target the gastric parietal cells, which are cells in the stomach lining. It can help diagnose autoimmune gastritis and pernicious anemia.

Mitochondrial Antibodies: Mitochondrial antibodies (MAs) are autoantibodies produced by the immune system that target the body's own mitochondria, the structures within cells that produce energy. The presence of MAs in the blood can suggest autoimmune diseases, especially Primary Biliary Cirrhosis (PBC), a liver disease, and can also indicate a higher risk for other conditions like Type 1 Diabetes.

Smooth Muscle Antibodies: Smooth Muscle Antibodies (SMAs) are autoantibodies that target proteins found in smooth muscle tissues. The presence of SMAs in the blood is often associated with autoimmune liver diseases such as autoimmune hepatitis and primary biliary cirrhosis. These conditions can cause a variety of symptoms including fatigue, jaundice, and abdominal pain.

Thyroid Peroxidase Antibodies: Thyroid peroxidase antibodies (TPO antibodies) are autoantibodies produced by the immune system that target thyroid peroxidase, an enzyme involved in thyroid hormone production. The presence of TPO antibodies in the blood can indicate an autoimmune thyroid disorder, such as Hashimoto's disease or Graves' disease.

Liver Kidney Microsomal (LKM) Antibodies: Liver Kidney Microsomal (LKM) Antibodies are a type of autoantibody produced by the immune system that target enzymes found in the liver and kidneys, potentially leading to inflammation and damage in these organs.